Louisiana is the 31st most extensive and the 25th most populous of the 50 United States. Its capital is Baton Rouge and largest city is New Orleans. Louisiana is the only state in the U.S. with political subdivisions termed parishes, which are local governments equivalent to counties. The largest parish by population is East Baton Rouge Parish, and the largest by land area is Plaquemines.

Much of the state's lands were formed from sediment washed down the Mississippi River, leaving enormous deltas and vast areas of coastal marsh and swamp. The two "Deltas" are located in Monroe, the parish seat of Ouachita Parish, Shreveport, the parish seat of Caddo Parish, and Alexandria, the parish seat of Rapides Parish, for the small Delta, and Monroe, Lake Charles, and New Orleans for the large Delta. They are referred to as Deltas because they form a perfect triangle shape when the points are lined up. These contain a rich southern biota; typical examples include birds such as ibis and egrets. There are also many species of tree frogs, and fish such as sturgeon and paddlefish. In more elevated areas, fire is a natural process in the landscape, and has produced extensive areas of longleaf pine forest and wet savannas. These support an exceptionally large number of plant species, including many species of orchids and carnivorous plants.

Some Louisiana urban environments have a multicultural, multilingual heritage, being so strongly influenced by a mixture of 18th-century French, Spanish, Native American, and African cultures that they are considered to be exceptional in the US. Before the American purchase of the territory in 1803, the current Louisiana State had been both a French colony and a Spanish one. In addition, colonists imported numerous African slaves as laborers in the 18th century. Many came from peoples of the same region of West Africa, thus concentrating their culture. In the post-Civil War environment, Anglo-Americans increased the pressure for Anglicization, and in 1915, English was made the only official language of the state. Louisiana has more Native American tribes than any other southern state, including four that are federally recognized, ten that are state recognized, and four that have not yet received recognition.